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KMID : 0043320070300030282
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Archives of Pharmacal Research
2007 Volume.30 No. 3 p.282 ~ p.289
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Modification of C2 Functional Group on Asiatic Acid and the Evaluation of Hepatoprotective Effects
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Jeong Byeong-Seon
Lee Mi-Kyeong
Kim Young-Choong
Lee Eung-Seok
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Abstract
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For the development of novel hepatoprotective agents, C2 functional group on asiatic acid was modified, and evaluated for their hepatoprotective effects. Among prepared compounds, compounds 10 and 14 showed better hepatoprotective effects compared to silymarin.
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KEYWORD
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Asiatic acid, Hepatoprotective effect, Structural modification
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